KOL Lecture Series
You can watch the recordings of the entire KOL Lecture Series on our YouTube channel.
2023
- Feb 2023: Considerations for Bayesian Methods with Informative Priors presented by James Travis
- Mar 2023: Using meta-analyses to guide statistical methodology for clinical dose response studies presented by Neal Thomas
- Apr 2023: The Bayesian Time Machine: Accounting for temporal drift in multi-arm platform trials presented by Ben Saville
- May 2023: Design and Sample Size Determination for Multiple-dose Randomized Phase II Trials for Dose Optimization presented by Ying Yuan
- Jul 2023: Why are there not more Bayesian Clinical Trials? Results from a Survey of Clinicians in the Clinical Trial Community presented by Jennifer Clark and Ross Bray
2022
- Jan 2022: Use of external data in randomized clinical trials presented by Heinz Schmidli and Marius Thomas, Novartis
- Mar 2022: Rev. Bayes’ best friend: Markov or Laplace? presented by Krishna Padmanabhan
- Apr 2022: Statistical Designs for Early Phase Oncology Drug Development in the Era of Dose Optimizing for Targeted Therapeutics presented by Yuan Ji
- May 2022: Bayesian Divide-and-Conquer Propensity Score Based Approaches for Leveraging Real World Data in Single Arm Clinical Trials presented by Jian Zhu and Eric Baron
- Jul 2022: A Bayesian Adaptive Trial in Duchenne Muscular Dystrophy presented by Stephen Lake
- Aug 2022: Delivering Transformative Medicines to Patients by Leveraging Complex Innovative Designs AMG 592 SLE Case Study presented by Amy Xia, May Mo, Tony Jiang
- Aug 2022: The Epistemological Superiority of Bayesian Inference over Frequentist Inference Inferring What is Likely To Be True presented by Stephen J. Ruberg
- Sep 2022: Case Study of a Phase 3 Study Design with Hybrid Control in 1L DLBCL: FDA Complex Innovative Designs Pilot Program presented by Jiawen Zhu & Herb Pang
- Oct 2022: Learnings from Chronic Pain Master Protocol: FDA Complex Innovative Designs Pilot Program presented by Saptarshi Chatterjee and Phebe Kemmer
- Nov 2022: NEOS: A Bayesian non-inferiority trial design in pediatric multiple sclerosis in the FDA Complex Innovative Designs Pilot Program presented by Marius Thomas & Dieter A Häring
- Dec 2022: CID from pilot program, to program, to common submission presented by Scott Berry
2021
- Feb 2021: Strategies for improving the assessment of the probability of success in late stage drug development presented by Lisa Hampson and Björn Holzhauer
- Mar 2021: Historical control data borrowing for non-inferiority assessment presented by Hui Quan
- Apr 2021: Bayesian multivariate probability of success with strict control of type I error presented by Matt Psioda and Ethan Alt
- Jun 2021: Bayesian detection of potential safety signal from blinded clinical trial data presented by Saurabh Mukhopadhyay and Brian Waterhouse
- Aug 2021: Bayesian Model Averaging of Longitudinal Dose Response Models presented by Richard Payne
- Oct 2021: Bayesian Shared Parameter Analysis of Mortality and Function within an Adaptive Platform Trial for ALS presented by Melanie Quintana
- Nov 2021: Use of Bayesian Hierarchical Models in the Presentation of Subgroup Analyses presented by Mark Rothmann
2020
- Aug 2020: DIA KOL Lectures presented by Alex Karanevich, PhD (EMB Statistical Solutions); Hengrui Sun, DrPH, MD (FDA); Joe Marion, PhD (Berry Consultants)
- Sep 2020: A Bayesian Sequential Design for COVID-19 Vaccine Trials presented by Rajat Mukherjee
- Oct 2020: Incorporate External Control Data in New Clinical Trial Design and Analysis presented by Lanju Zhang, PhD (AbbVie)
- Nov 2020: Leveraging External Evidence in Medical Device Decision-Making presented by Ram Tiwari
- Dec 2020: Statistical considerations for trials that study multiple indications presented by Brian Hobbs; Emily Zabor; Alexander Kaizer
2019
- Feb 2019: Case Studies in Calibrating Hierarchical Model Priors presented by Kert Viele
- Mar 2019: Bayesian Biopharmaceutical Applications using PROC MCMC and PROC BGLIMM presented by Fang Chen
- Jul 2019: Nonclinical Bayesian projects AZ presented by Steven Novick
- Aug 2019: Why Bother with Bayes presented by Thomas Louis
- Sep 2019: Why Bayes for Clinical Trials presented by Frank Harrell
- Oct 2019: Benefit Risk Assessment Using Bayesian Discrete Choice Experiment presented by Saurabh Mukhopadhyay
- Nov 2019: Use of Historical Data in Clinical Trial: An Evidence Synthesis Approach presented by Satrajit Roychoudhury (Pfizer Inc) and Sebastian Weber (Novartis)
2018
- Jan 2018: The Value of Bayesian Approaches in the Regulatory Setting: Lessons from the Past and Perspectives for the Future presented by Telba Irony
- Mar 2018: Design and analysis of non-inferiority trials: some frequentist and Bayesian perspective presented by Samiran Ghosh
- Aug 2018: Bayesian sample size determination methods for hypotheses testing presented by Sujit Ghosh
- Oct 2018: Unified Screening for Potential Elevated Adverse Event Risk and Other Associations presented by Larry Gould
- Dec 2018: BOIN: a Novel Platform for Designing Early Phase Clinical Trials presented by Ying Yuan
2017
- Jun 2017: Bayesian Methods in Pharmaceutical Development and Clinical Trial Design presented by Scott Berry
- Aug 2017: Bayesian Disease Progression Modeling in Clinical Trial Design presented by Melanie Quintana
- Oct 2017: BMA-Mod : A Bayesian Model Averaging Strategy for Determining Dose-Response Relationships in the Presence of Model Uncertainty presented by Larry Gould